Diffusion Tensor Imaging (DTI) studies are increasingly popular among clinicians and researchers as they provide unique insights into brain network connectivity. However, in order to optimize the use of DTI, several technical and methodological aspects must be factored in. These include decisions on: acquisition protocol, artifact handling, data quality control, reconstruction algorithm, and visualization approaches, and quantitative analysis methodology. Furthermore, the researcher and/or clinician also needs to take into account and decide on the most suited software tool(s) for each stage of the DTI analysis pipeline. Herein, we provide a straightforward hitchhiker's guide, covering all of the workflow's major stages. Ultimately, this guide will help newcomers navigate the most critical roadblocks in the analysis and further encourage the use of DTI.
Vanishing hitchhiker stories as we now tell them date to the turn of the century, but their predecessors go back centuries before that. As time rolled on, the wagons and horses of older times transformed into the cars of today.
According to folklorist Jan Brunvand, the legend of the vanishing hitchhiker evolved from earlier European stories, usually about travelers on horseback. In Hawaii, the hitchhiker became associated with the ancient volcano goddess Pele. A prototype of the story shows up in the New Testament (Acts 8:26-39), in which an Ethiopian driving a chariot picks up the Apostle Philip, who baptizes him and then disappears.
The most common version of the legend involves a driver who stops for a strange girl on a highway, then during the course of the ride realizes his hitchhiker has disappeared. Upon arriving at the address the girl had mentioned, the driver learns from her relatives that she has been dead for years:
Another popular version stars a hitchhiker who makes a prophesy before vanishing in front of the driver's eyes. Good crops, the end of a war, a natural catastrophe about to strike, or the imminent coming of Jesus have been predicted by these vanishing prophets. At the completion of some of these tales, the driver seeks out the police to report the incident and is told he's the fourth person this has happened to this week.
The vanishing prophet set of stories contains a smaller subset in which the prediction of one future event is bolstered by the prediction of a second, equally unbelievable, event which subsequently comes true. The hitchhiker sometimes vanishes after making the predictions:
Vanishing hitchhikers appear in numerous songs and in the 1951 Orson Welles' short film Return to Glennascaul, the 1985 movie Mr. Wrong, and the 1824 Washington Irving novel The Lady With The Velvet Collar. In 1998 K-Mart ran a vanishing hitchhiker commercial to advertise its Route 66 jeans.
(English pronunciations of hitchhiker from the Cambridge Advanced Learner's Dictionary & Thesaurus and from the Cambridge Academic Content Dictionary, both sources Cambridge University Press) 076b4e4f54